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Clean ingredients. clinical results.

What we found

  • 94 %

    of participants saw a decrease in feelings of upset stomach 30 minutes after taking Hilma Occasional Heartburn + Indigestion Relief*

  • 79 %

    of participants saw a decrease in feelings of occasional head tension 30 minutes after taking Hilma Tension Relief*

At Hilma, we do homework—not guesswork.

WORLD-CLASS EXPERTS

Doctors & researchers behind the studies

WORLD-CLASS EXPERTS

Doctors & researchers behind the studies

We recruited Dr. Soyona Rafatjah, an MD with both traditional and holistic medical experience….

We recruited Dr. Soyona Rafatjah, an MD with both traditional and holistic medical experience, to be the Principal Investigator of our trial. We then teamed up with innovative Contract Research Organization, The Hawthorne Effect, led by Jodi Akin, to administer the trials. All trials were approved with a third-party Institutional Review Board, Advarra, and were prospectively registered on clinicaltrial.gov. 

Meet the team

We recruited Dr. Soyona Rafatjah, an MD with both traditional and holistic medical experience, to be the Principal Investigator of our trial. We then teamed up with innovative Contract Research Organization, The Hawthorne Effect, led by Jodi Akin, to administer the trials. All trials were approved with a third-party Institutional Review Board, Advarra, and were prospectively registered on clinicaltrial.gov. 

The participants

70+ completed participants per study

The participants

70+ completed participants per study

We had 101 participants for our Occasional Heartburn + Indigestion trial, 79 participants for our Tension Relief trial…

We had 101 participants for our Upset Stomach trial, 79 participants for our Tension Relief trial, and 74 participants for our Immune Support trial. All our participants are healthy adult men and women ages 20-65+ who met our predefined criteria of participation.

keep reading

We had 101 participants for our Upset Stomach trial, 79 participants for our Tension Relief trial, and 74 participants for our Immune Support trial. All our participants are healthy adult men and women ages 20-65+ who met our predefined criteria of participation.

The study design

Single-arm observational studies

The study design

Single-arm observational studies

We ran three-single arm observational studies, which means that we sent participants…

We ran three-single arm observational studies, which means that we sent participants unbranded products and asked that they take them after a specific trigger. Once they experienced the trigger, they took the product and recorded how their body coped. These studies are foundational and investigative research, which establish a baseline for our products’ performance. The next step for further investment would be to do double blind placebo-controlled studies.

our process

We ran three-single arm observational studies, which means that we sent participants unbranded products and asked that they take them after a specific trigger. Once they experienced the trigger, they took the product and recorded how their body coped. These studies are foundational and investigative research, which establish a baseline for our products’ performance. The next step for further investment would be to do double blind placebo-controlled studies.

We did the research so we could show you results.

Select Study:

Upset stomach relief bottle with herbs and other ingredients over a purple background Upset stomach relief bottle with herbs and other ingredients over a purple background

Occasional Heartburn + Indigestion Relief

No. Participants

101

Age of Participants

20 - 65+

We ran a single-arm observational study on Occasional Heartburn + Indigestion Relief. Participants opted in who met the predefined criteria. They were sent our product (unbranded) and asked to take it after a specific trigger. They recorded how their body coped. These studies are foundational and investigative research, which establish a baseline for product performance.

Made From: Chamomile, Artichoke Leaf, Ginger Root, Licorice (DGL Extract), Marshmallow Root

“I believe every supplement company should be rigorously studying the effects of their products—yet very few actually do.”

— Dr. Soyona Rafatjah

94% of participants saw a decrease in feelings of upset stomach in 30 minutes.*

Based on a 4-point Likert scale: a validated scale designed to assess perceived levels of discomfort.

Based on a 4-point Likert scale: a validated scale designed to assess perceived levels of discomfort.

Upset Stomach

The composite upset stomach score is a general summary score that is the average of specific scores on a pre-defined scale which includes (but is not limited to) feelings of bloating, early fullness during a meal, discomfort in the upper abdomen, burping, as well as a few others.

Upset Stomach

The composite upset stomach score is a general summary score that is the average of specific scores on a pre-defined scale which includes (but is not limited to) feelings of bloating, early fullness during a meal, discomfort in the upper abdomen, burping, as well as a few others.

Tension relief surrounded by natural ingredients in the product Tension relief surrounded by natural ingredients in the product

Tension Relief

No. Participants

79

Age of Participants

20 - 65+

We ran a single-arm observational study on Tension Relief. Participants opted in who experience occasional head tension and met the predefined criteria. They were sent our product (unbranded) and asked to take it after a specific trigger. They recorded how their body coped at different time intervals. These studies are foundational and investigative research, which establish a baseline for product performance. The next step for further investment would be double-blind placebo-controlled studies.

Made From: White Willow Bark, Magnesium, Boswellia, Feverfew, Skullcap

“I believe every supplement company should be rigorously studying the effects of their products—yet very few actually do.”

— Dr. Soyona Rafatjah

79% of participants saw a decrease in feelings of occasional head tension after 30 minutes.*

Tension is measured on 10-point predefined scale. The values range from 0 (Tension Free) to 10 (Significant Tension)

Tension is measured on 10-point predefined scale. The values range from 0 (Tension Free) to 10 (Significant Tension)

Occasional Heartburn + Indigestion Relief

No. Participants

101

Age of Participants

20 - 65+

We ran a single-arm observational study on Occasional Heartburn + Indigestion Relief. Participants opted in who met the predefined criteria. They were sent our product (unbranded) and asked to take it after a specific trigger. They recorded how their body coped. These studies are foundational and investigative research, which establish a baseline for product performance.

Made From: Chamomile, Artichoke Leaf, Ginger Root, Licorice (DGL Extract), Marshmallow Root

Made From: Chamomile, Artichoke Leaf, Ginger Root, Licorice (DGL Extract), Marshmallow Root

94% of participants saw a decrease in feelings of upset stomach in 30 minutes.*

Based on a 4-point Likert scale: a validated scale designed to assess perceived levels of discomfort.

Based on a 4-point Likert scale: a validated scale designed to assess perceived levels of discomfort.

Upset Stomach

The composite upset stomach score is a general summary score that is the average of specific scores on a pre-defined scale which includes (but is not limited to) feelings of bloating, early fullness during a meal, discomfort in the upper abdomen, burping, as well as a few others.

Upset Stomach

The composite upset stomach score is a general summary score that is the average of specific scores on a pre-defined scale which includes (but is not limited to) feelings of bloating, early fullness during a meal, discomfort in the upper abdomen, burping, as well as a few others.

“I believe every supplement company should be rigorously studying the effects of their products—yet very few actually do.”

— Dr. Soyona Rafatjah

Tension Relief

No. Participants

79

Age of Participants

20 - 65+

We ran a single-arm observational study on Tension Relief. Participants opted in who experience occasional head tension and met the predefined criteria. They were sent our product (unbranded) and asked to take it after a specific trigger. They recorded how their body coped at different time intervals. These studies are foundational and investigative research, which establish a baseline for product performance. The next step for further investment would be double-blind placebo-controlled studies.

Made From: White Willow Bark, Magnesium, Boswellia, Feverfew, Skullcap

Made From: White Willow Bark, Magnesium, Boswellia, Feverfew, Skullcap

79% of participants saw a decrease in feelings of occasional head tension after 30 minutes.*

Tension is measured on 10-point predefined scale. The values range from 0 (Tension Free) to 10 (Significant Tension)

Tension is measured on 10-point predefined scale. The values range from 0 (Tension Free) to 10 (Significant Tension)

“I believe every supplement company should be rigorously studying the effects of their products—yet very few actually do.”

— Dr. Soyona Rafatjah

Our world-class experts. 

Our world-class experts. 

Dr. Soyona Rafatjah

Dr. Soyona Rafatjah is the Principle Investigator for Hilma’s clinical studies.

She is a board-certified Family Medicine physician and Medical Director and Co-Founder of PrimeHealth, and prior to starting PrimeHealth, she was a physician at Parsley Health in New York City, a technology-forward Functional Medicine practice where she was integral to its rapid growth.

Meet Soyona

Jodi Akin

Jodi is founder & CEO of The Hawthorne Effect, a clinical research organization built for modern clinical studies, with a mission to make clinical studies accessible to everyone, everywhere.

She has more than 20 years experience in clinical development, scientific and regulatory strategy, management and medtech market development.

Meet Jodi

Bill Anderson

William Anderson, PhD is a biostatistical consultant.

 For 25 years he was a faculty member at various universities. For the last 25 years he has worked in clinical trial statistics, both as an employee and as an independent consultant. The Hawthorne Effect is among his current consulting clients. He is an author or coauthor of over 75 papers in peer reviewed journals.

Meet Bill

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